HCPCS code J0640: Leucovorin injection, per 50 mg2026 Medicare rate & RVUs in Oregon
Leucovorin calcium injection is used for methotrexate rescue and with fluorouracil; Medicare does not accept J0640 for reporting.
CMS doesn’t publish an office rate for J0640 in Oregon.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
Your location
On this page 9 sections
What J0640 covers
Leucovorin calcium, a form of folinic acid, is given by injection, usually intravenously or intramuscularly. Oncology teams use it to reduce the effects of methotrexate, and some chemotherapy regimens pair it with fluorouracil. The drug may be administered as part of cancer treatment or methotrexate rescue.
J0640 has Medicare physician fee schedule status I, meaning it is not a valid Medicare reporting code and Medicare uses a different code for the service. Its unit definition is 50 mg of leucovorin calcium, but that unit basis does not make J0640 valid for Medicare claims. The HCPCS pricing classification is Part B drug; when covered, Medicare generally pays from CMS quarterly Average Sales Price drug pricing files. Special Medicare coverage instructions apply.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where J0640 pays more and less in Oregon
| Payment locality | Office | Facility |
|---|---|---|
| Portland, OR | Unavailable | Unavailable |
| Rest of Oregon | Unavailable | Unavailable |
How the J0640 rate is calculated
Each of J0640’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · J0640
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense0.00
0.00 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
0.0000
Conversion factor
$33.4009
Medicare rate
$0.00
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for J0640
J0640 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.
Place of service · J0640
Which rate does Medicare pay?
The POS code on the claim line (CMS-1500 box 24B).
POS 11 · non-facility rate · national
—
J0640 isn’t priced in this setting.
J0640 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- J0643Leucovorin injectionPer 1 mg
- J0643 identifies leucovorin calcium in 1 mg units; J0640 has a 50 mg unit basis and is not valid for Medicare reporting.
- J0641Levoleucovorin injectionPer 0.5 mg
- J0641 is for levoleucovorin, not leucovorin calcium. Choose based on the drug administered rather than treating the codes as interchangeable.
- J0644Avyxa leucovorinPer 1 mg
- J0644 identifies product-specific Avyxa leucovorin calcium. J0640 has a 50 mg unit basis and is not valid for Medicare reporting.
J0640 billing questions
Can J0640 be submitted to Medicare for leucovorin calcium?
No. J0640 has Medicare status I and is not valid for Medicare reporting; Medicare uses a different code for this service.
How does J0640 differ from J0643?
Both identify injectable leucovorin calcium, but J0640 has a 50 mg unit basis and J0643 has a 1 mg unit basis.
What does one J0640 unit represent?
One unit represents 50 mg of leucovorin calcium. J0640 is not valid for Medicare reporting.
How does J0641 differ from J0640?
J0641 identifies levoleucovorin, a distinct drug. Select the code for the drug administered rather than treating the two drugs as interchangeable.
How does Medicare classify leucovorin calcium for payment?
The HCPCS pricing classification is Part B drug; when covered, Medicare generally pays from CMS quarterly ASP drug pricing files. J0640 itself is not valid for Medicare reporting, and special coverage instructions apply.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Fee sheets · Coming soon
Put J0640 and the rest of your codes on one sheet
Your codes at your locality, with payer contracts beside Medicare.
Join the waitlist