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HCPCS code J0643: Leucovorin injection, per 1 mg2026 Medicare rate & RVUs in New Mexico

Injectable leucovorin calcium is reported in 1 mg units for methotrexate rescue or as part of certain fluorouracil cancer regimens.

CMS RVU26DEffective Oct 1, 2026One payment locality

CMS doesn’t publish a rate for J0643 in New Mexico.

Separate payment rules applyOffice (non-facility)
Separate payment rules applyHospital or facility

Check a contract rate as a % of Medicare · J0643 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open J0643 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in New Mexico
  2. What J0643 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What J0643 covers

J0643 identifies injectable leucovorin calcium not otherwise specified. Leucovorin is used as rescue after high-dose methotrexate and alongside fluorouracil in cancer treatment. Oncology clinicians administer it by injection, commonly in outpatient oncology offices and infusion centers. Choose the appropriate leucovorin code for the product supplied; J0643 is the not-otherwise-specified option.

One unit represents 1 mg of leucovorin calcium, so reported units match the administered milligram dose. CMS assigns physician fee schedule status E, excluding J0643 from the physician fee schedule by regulation. When Medicare covers the drug, payment is under another method; as a Part B drug, it is generally priced using CMS quarterly Average Sales Price drug pricing files. Special Medicare coverage instructions apply.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How New Mexico compares for J0643

J0643 in New Mexico vs other payment areas
  1. New Mexico · this pageUnavailable
  2. Los Angeles, CA · CaliforniaUnavailable
  3. Washington, DC area · District of ColumbiaUnavailable
  4. Miami, FL · FloridaUnavailable
  5. Chicago, IL · IllinoisUnavailable
  6. Manhattan, NY · New YorkUnavailable
  7. Alaska · AlaskaUnavailable

Other areas in New Mexico first, then benchmark localities. Bars start at $0.

Every other payment area

J0643 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama——
ArkansasArkansas——
ArizonaArizona——
Bakersfield, CACalifornia——
Chico, CACalifornia——
El Centro, CACalifornia——
Fresno, CACalifornia——
Hanford, CACalifornia——

J0643 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
J0643 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

See J0643 in every payment locality

How the J0643 rate is calculated

Each of J0643’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · J0643

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for J0643

J0643 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · J0643

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

J0643 isn’t priced in this setting.

Codes related to J0643

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to J0643
CodeHow it relatesOffice range, New Mexico
Same family
J0640Leucovorin injection, per 50 mgAnother HCPCS code for leucovorin calcium injection.No office rate
J0644Avyxa leucovorin, per 1 mgIdentifies the Avyxa leucovorin calcium product.No office rate
Used instead
J0641Levoleucovorin injection, per 0.5 mgIdentifies levoleucovorin, a different injectable used in similar treatment settings.No office rate
J0642Levoleucovorin injection, khapzory, per 0.5 mgIdentifies the Khapzory levoleucovorin product rather than leucovorin calcium.No office rate

How J0643 has changed in New Mexico

J0643 · Office / nonfacility

Rate unavailable

Effective 2026-10-01

A rate is unavailable in one of these releases, so a change cannot be calculated.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. October 1, 2026

    RVU26D

    No ratechanged toNo rate

  2. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D, RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D, RVU24A, RVU24AR, RVU24B, RVU24C, RVU24D, RVU25A, RVU25B, RVU25C, RVU25D, RVU26A, RVU26B, RVU26C.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01Separate payment rules applySeparate payment rules applyRVU26D
2026-07-01Not in this releaseNot in this releaseRVU26C
2026-04-01Not in this releaseNot in this releaseRVU26B
2026-01-01Not in this releaseNot in this releaseRVU26A
2025-10-01Not in this releaseNot in this releaseRVU25D
2025-07-01Not in this releaseNot in this releaseRVU25C
2025-04-01Not in this releaseNot in this releaseRVU25B
2025-01-01Not in this releaseNot in this releaseRVU25A
2024-10-01Not in this releaseNot in this releaseRVU24D
2024-07-01Not in this releaseNot in this releaseRVU24C
2024-04-01Not in this releaseNot in this releaseRVU24B
2024-03-09Not in this releaseNot in this releaseRVU24AR
2024-01-01Not in this releaseNot in this releaseRVU24A
2023-10-01Not in this releaseNot in this releaseRVU23D
2023-07-01Not in this releaseNot in this releaseRVU23C
2023-04-01Not in this releaseNot in this releaseRVU23B
2023-01-01Not in this releaseNot in this releaseRVU23A
2022-10-01Not in this releaseNot in this releaseRVU22D
2022-07-01Not in this releaseNot in this releaseRVU22C
2022-04-01Not in this releaseNot in this releaseRVU22B
2022-01-01Not in this releaseNot in this releaseRVU22A
2021-10-01Not in this releaseNot in this releaseRVU21D
2021-07-01Not in this releaseNot in this releaseRVU21C
2021-04-01Not in this releaseNot in this releaseRVU21B
2021-01-01Not in this releaseNot in this releaseRVU21A
2020-10-01Not in this releaseNot in this releaseRVU20D
2020-07-01Not in this releaseNot in this releaseRVU20C
2020-04-01Not in this releaseNot in this releaseRVU20B
2020-01-01Not in this releaseNot in this releaseRVU20A
2019-10-01Not in this releaseNot in this releaseRVU19D
2019-07-01Not in this releaseNot in this releaseRVU19C
2019-04-01Not in this releaseNot in this releaseRVU19B
2019-01-01Not in this releaseNot in this releaseRVU19A
2018-10-01Not in this releaseNot in this releaseRVU18D
2018-07-01Not in this releaseNot in this releaseRVU18C
2018-04-01Not in this releaseNot in this releaseRVU18B
2018-01-01Not in this releaseNot in this releaseRVU18AR1
2017-10-01Not in this releaseNot in this releaseRVU17D
2017-07-01Not in this releaseNot in this releaseRVU17C
2017-04-01Not in this releaseNot in this releaseRVU17B
2017-01-01Not in this releaseNot in this releaseRVU17A
2016-10-01Not in this releaseNot in this releaseRVU16D
2016-07-01Not in this releaseNot in this releaseRVU16C
2016-04-01Not in this releaseNot in this releaseRVU16B
2016-01-01Not in this releaseNot in this releaseRVU16A
2015-10-01Not in this releaseNot in this releaseRVU15D
2015-07-01Not in this releaseNot in this releaseRVU15C
2015-04-01Not in this releaseNot in this releaseRVU15B
2015-01-01Not in this releaseNot in this releaseRVU15A
2014-10-01Not in this releaseNot in this releaseRVU14D
2014-07-01Not in this releaseNot in this releaseRVU14C
2014-04-01Not in this releaseNot in this releaseRVU14B
2014-01-01Not in this releaseNot in this releaseRVU14A
2013-10-01Not in this releaseNot in this releaseRVU13D
2013-07-01Not in this releaseNot in this releaseRVU13C
2013-04-01Not in this releaseNot in this releaseRVU13B
2013-01-01Not in this releaseNot in this releaseRVU13AR

Price J0643 for an earlier date of service

Where the New Mexico rate applies

New Mexico is a Medicare payment area, not a city. Our Census mapping connects it to 528 cities and communities in New Mexico. Some span more than one payment area; confirm with the service ZIP.

  • Abeytas
  • Abiquiu
  • Acomita Lake
  • Adelino
  • Agua Fria
  • Alamillo
  • Alamo
  • Alamogordo

Browse all communities in New Mexico

J0643 billing questions

What does one J0643 unit represent?

One unit represents 1 mg of leucovorin calcium. Report units to match the administered dose in milligrams.

How is J0643 different from J0640?

Both codes identify leucovorin calcium injection. J0643 specifies a 1 mg unit; select the code that matches the product and applicable HCPCS descriptor.

When should J0643 be distinguished from J0644?

J0643 is the not-otherwise-specified leucovorin calcium code. J0644 identifies the Avyxa product.

Is J0643 the code for levoleucovorin?

No. J0643 is for leucovorin calcium. J0641 and J0642 identify levoleucovorin products.

How does Medicare treat J0643?

Its physician fee schedule status is E, so it is excluded from the physician fee schedule. When covered, it is paid under another method; as a Part B drug, it is generally priced using CMS quarterly ASP drug pricing files. Special Medicare coverage instructions apply.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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