HCPCS code Q4301: Wound matrix, activate Matrix, per square centimeter2026 Medicare rate & RVUs in South Dakota

Q4301 reports Activate Matrix by square centimeter when a clinician applies this specific matrix as part of a wound treatment procedure.

CMS RVU26DEffective Oct 1, 2026One payment locality

In South Dakota, Medicare pays $127.26 for Q4301 in the office.

$127.26Office (non-facility)
Not available in this settingHospital or facility
+0.0%vs the national office rate ($127.26)

Check a contract rate as a % of Medicare · Q4301 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4301 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Dakota
  2. What Q4301 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What Q4301 covers

Activate Matrix is a named wound matrix supplied for placement on a prepared wound bed. A wound-care clinician may use it during a skin-substitute application procedure, such as treatment of a lower-extremity wound. Q4301 identifies the product, not the work of preparing the wound and applying the matrix. The record should identify Activate Matrix by name and show where it was placed.

Report Q4301 in square-centimeter units supported by the product-use record, rather than counting wounds or packages. Document the wound location and measurements, the amount of Activate Matrix used, and the associated application procedure. CMS classifies Q4301 as an add-on code: it is billed with a primary procedure, and its payment falls within that procedure’s global period. CMS also designates Q4301 as technical-component-only; a separately reportable interpretation is represented by another code, not by Q4301. Select a different product code if the material used was not Activate Matrix.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Dakota compares for Q4301

Across 109 of 109 payment localities, the office rate for Q4301 runs from $109.31 in Arkansas to $183.51 in Santa Clara County, CA. South Dakota pays $127.26. The RVUs are the same everywhere; the geographic indexes change the dollars.

Q4301 in South Dakota vs other payment areas
  1. South Dakota · this page$127.26
  2. Los Angeles, CA · California$150.55+$23.29
  3. Washington, DC area · District of Columbia$149.91+$22.65
  4. Miami, FL · Florida$132.47+$5.21
  5. Chicago, IL · Illinois$127.89+$0.63
  6. Manhattan, NY · New York$147.87+$20.61
  7. Alaska · Alaska$135.53+$8.27

Other areas in South Dakota first, then benchmark localities. Bars start at $0.

Every other payment area

Q4301 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$111.35—
ArkansasArkansas$109.31—
ArizonaArizona$123.31—
Bakersfield, CACalifornia$139.47—
Chico, CACalifornia$139.47—
El Centro, CACalifornia$139.47—
Fresno, CACalifornia$139.47—
Hanford, CACalifornia$139.47—

Q4301 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4301 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

See Q4301 in every payment locality

How the Q4301 rate is calculated

Each of Q4301’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4301

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Dakota inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

18,388

Code
Q4301
Physician work
0.00
Practice expense
3.81
Malpractice
0.00

GPCI2026.csv

94

Locality
South Dakota
Physician work
1.000
Practice expense
1.000
Malpractice
0.336
Office calculation for Q4301 in South Dakota
ComponentRVULocality factorAdjusted
Physician work0.00× 1.0000.0000
Practice expense3.81× 1.0003.8100
Malpractice0.00× 0.3360.0000
Total RVUs3.8100
Conversion factor× 33.4009

Office rate, South Dakota$127.26

Office: (0 × 1 + 3.81 × 1 + 0 × 0.336) × $33.4009 = $127.26

Open Q4301 in the RVU calculator

Payment rules and modifiers for Q4301

The CMS indicators that decide how Q4301 is paid alongside other services.

CMS payment indicators · Q4301

Wound matrix, activate Matrix, per square centimeter

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

How Q4301 has changed in South Dakota

Q4301 · Office / nonfacility

$127.26

Effective 2026-10-01

A rate is unavailable in one of these releases, so a change cannot be calculated.

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    No ratechanged to$127.26

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2024

    RVU24A

    No ratechanged toNo rate

    Held through RVU24AR, RVU24B, RVU24C, RVU24D, RVU25A, RVU25B, RVU25C, RVU25D.

  3. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D, RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$127.26Not available in this settingRVU26D
2026-07-01$127.26Not available in this settingRVU26C
2026-04-01$127.26Not available in this settingRVU26B
2026-01-01$127.26Not available in this settingRVU26A
2025-10-01Separate payment rules applySeparate payment rules applyRVU25D
2025-07-01Separate payment rules applySeparate payment rules applyRVU25C
2025-04-01Separate payment rules applySeparate payment rules applyRVU25B
2025-01-01Separate payment rules applySeparate payment rules applyRVU25A
2024-10-01Separate payment rules applySeparate payment rules applyRVU24D
2024-07-01Separate payment rules applySeparate payment rules applyRVU24C
2024-04-01Separate payment rules applySeparate payment rules applyRVU24B
2024-03-09Separate payment rules applySeparate payment rules applyRVU24AR
2024-01-01Separate payment rules applySeparate payment rules applyRVU24A
2023-10-01Not in this releaseNot in this releaseRVU23D
2023-07-01Not in this releaseNot in this releaseRVU23C
2023-04-01Not in this releaseNot in this releaseRVU23B
2023-01-01Not in this releaseNot in this releaseRVU23A
2022-10-01Not in this releaseNot in this releaseRVU22D
2022-07-01Not in this releaseNot in this releaseRVU22C
2022-04-01Not in this releaseNot in this releaseRVU22B
2022-01-01Not in this releaseNot in this releaseRVU22A
2021-10-01Not in this releaseNot in this releaseRVU21D
2021-07-01Not in this releaseNot in this releaseRVU21C
2021-04-01Not in this releaseNot in this releaseRVU21B
2021-01-01Not in this releaseNot in this releaseRVU21A
2020-10-01Not in this releaseNot in this releaseRVU20D
2020-07-01Not in this releaseNot in this releaseRVU20C
2020-04-01Not in this releaseNot in this releaseRVU20B
2020-01-01Not in this releaseNot in this releaseRVU20A
2019-10-01Not in this releaseNot in this releaseRVU19D
2019-07-01Not in this releaseNot in this releaseRVU19C
2019-04-01Not in this releaseNot in this releaseRVU19B
2019-01-01Not in this releaseNot in this releaseRVU19A
2018-10-01Not in this releaseNot in this releaseRVU18D
2018-07-01Not in this releaseNot in this releaseRVU18C
2018-04-01Not in this releaseNot in this releaseRVU18B
2018-01-01Not in this releaseNot in this releaseRVU18AR1
2017-10-01Not in this releaseNot in this releaseRVU17D
2017-07-01Not in this releaseNot in this releaseRVU17C
2017-04-01Not in this releaseNot in this releaseRVU17B
2017-01-01Not in this releaseNot in this releaseRVU17A
2016-10-01Not in this releaseNot in this releaseRVU16D
2016-07-01Not in this releaseNot in this releaseRVU16C
2016-04-01Not in this releaseNot in this releaseRVU16B
2016-01-01Not in this releaseNot in this releaseRVU16A
2015-10-01Not in this releaseNot in this releaseRVU15D
2015-07-01Not in this releaseNot in this releaseRVU15C
2015-04-01Not in this releaseNot in this releaseRVU15B
2015-01-01Not in this releaseNot in this releaseRVU15A
2014-10-01Not in this releaseNot in this releaseRVU14D
2014-07-01Not in this releaseNot in this releaseRVU14C
2014-04-01Not in this releaseNot in this releaseRVU14B
2014-01-01Not in this releaseNot in this releaseRVU14A
2013-10-01Not in this releaseNot in this releaseRVU13D
2013-07-01Not in this releaseNot in this releaseRVU13C
2013-04-01Not in this releaseNot in this releaseRVU13B
2013-01-01Not in this releaseNot in this releaseRVU13AR

Price Q4301 for an earlier date of service

Where the South Dakota rate applies

South Dakota is a Medicare payment area, not a city. Our Census mapping connects it to 485 cities and communities in South Dakota. Some span more than one payment area; confirm with the service ZIP.

  • Aberdeen
  • Agar
  • Agency Village
  • Akaska
  • Albee
  • Alcester
  • Alexandria
  • Allen

Browse all communities in South Dakota

Q4301 billing questions

When is Q4301 reported with a skin-substitute application code?

Report Q4301 for the Activate Matrix product when it is used with the documented primary application procedure. The application work is represented by the procedure code, not by Q4301.

How are units determined for Q4301?

Each unit represents one square centimeter of Activate Matrix. Use the documented product amount to support the units rather than the number of wounds treated.

Can Q4301 be billed by itself?

No. CMS classifies it as an add-on code billed with a primary procedure; its payment is within that procedure’s global period.

Does Q4301 include interpretation?

No. CMS designates Q4301 as technical-component-only and identifies a separate code for interpretation.

How does Q4301 differ from Q4309?

Choose by the product actually documented: Q4301 identifies Activate Matrix, while Q4309 identifies Via Matrix.

What documentation distinguishes Q4301 from other wound-product codes?

The record should name Activate Matrix, identify the treated site, and support the square centimeters billed. A generic entry such as “wound matrix applied” does not identify this product.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4301PPRRVU2026_Oct_nonQPP.csv, line 18,388 (RVU26D)
Geographic factors for South DakotaGPCI2026.csv, line 94 (RVU26D)

Open CMS sourceHow we calculate rates

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