HCPCS Q4161: Wound productMedicare rate & RVUs

Q4161 reports Bio-connekt wound product by square centimeter when it is supplied with a primary wound-treatment procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4161 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4161

Wound product

Swap in your local Medicare rate.

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4161 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4161 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4161 covers

Q4161 identifies Bio-connekt, a wound-care product measured by the area supplied. It is reported in settings where a clinician treats a wound and uses the product as part of that care. The code represents the product, not the clinical work of preparing or applying it. The primary procedure describes the wound treatment; the product code accounts for Bio-connekt separately.

Report the quantity in square centimeters and support it with documentation identifying Bio-connekt and the amount used. CMS classifies Q4161 as an add-on: it must be billed with a primary procedure, and its payment is included within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation. Keep the product quantity distinct from the primary procedure’s service reporting, and use the HCPCS code that identifies the product actually furnished.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4161 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4161 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4161 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4161 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4161 rate is calculated

Each of Q4161’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4161

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4161

The CMS indicators that decide how Q4161 is paid alongside other services.

CMS payment indicators · Q4161

Wound product

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4161 compared with similar codes

Compare codes

Q4161 vs 15271 vs Q4160 vs Q4159 vs Q4151: national Medicare rates

Swap in your local Medicare rate.

  • Q4161
    Wound product · 0 wRVU
    $127.26
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73
  • Q4160
    Wound product · 0 wRVU
    $127.26+$0.00
  • Q4159
    Wound product · 0 wRVU
    $127.26+$0.00
  • Q4151
    Amniotic membrane · 0 wRVU
    $127.26+$0.00

How to choose

15271Skin substitute graft
15271 reports the primary skin-substitute application service; Q4161 identifies the Bio-connekt product supplied with a primary procedure.
Q4160Wound product
Q4160 identifies NuShield, while Q4161 identifies Bio-connekt. Select the product code that matches the material furnished.
Q4159Wound product
Q4159 identifies Affinity per square centimeter; Q4161 is specific to Bio-connekt.
Q4151Amniotic membrane
Q4151 identifies AmnioBand per square centimeter. It is a different product code, not an alternate description for Bio-connekt.

Q4161 billing questions

Can Q4161 be billed by itself?

No. CMS identifies Q4161 as an add-on code that must be reported with a primary procedure.

How should the quantity be reported?

Report Bio-connekt in square centimeters. Document the product and the amount used so the billed quantity is supported.

Is Q4161 the wound application procedure?

No. Q4161 identifies the Bio-connekt product; the primary procedure reports the wound treatment or application service.

How does the global-period rule affect payment?

CMS pays Q4161 within the global period of the primary procedure, so it is not paid as a separate service outside that procedure’s global period.

Does Q4161 include interpretation?

No. CMS classifies it as technical-component-only, with interpretation covered by a separate code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4161PPRRVU2026_Oct_nonQPP.csv, line 18,254 (RVU26D)

Open CMS sourceHow we calculate rates

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